25 August 2008

Hormone treatment may offer future hearing loss prevention

Swedish study indicating that simple treatment with oestrogen stimulating drugs may be useful in combating hearing loss.

The researchers studied the impact of the female oestrogen hormone. They found that one of two receptors the female oestrogen sex hormone binds itself to offers good protection against hearing loss in both males and females. The study was based on experiments with mice.

”We found that the beta (oestrogen) receptor protects against hearing loss”, said Barbara Canlon, a professor at the department of physiology and pharmacology at the Karolinska Institute in Stockholm.

The study indicated that treatment of hearing loss may be possible with a hormone treatment already on the market and currently used in the treatment of breast cancer, among other diseases.

Treatment with ER-beta binding drugs was found to protect the mice against hearing damage. The researchers concluded that the identification of an auditory-protective role for the ER-beta oestrogen receptor should make it possible to develop some form of hearing loss treatment for people. Much further research is needed before the possible development of such a new treatment.

Source: www.cordis.europa.eu.
Published on hear-it on August 25, 2008.